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#Selected Publications

Bold: from MRML
* First author
# Corresponding author

Cho Y*, Kim H*, Yook G*, Yong S, Kim S, Lee N, Kim YJ, Kim J, Kim TW, Chang MJ, Lee KM, Chang CB, Kang SB, Kim JH# (2024) IRF1 deficiency predisposes cartilage to accumulate DNA damage and promotes osteoarthritis development

Arthritis & Rheumatology

Suh J*, Kim H*, Min J, Yeon HJ, Hemberg M, Scimeca L, Wu MR, Kang HG, Kim YJ#, and Kim JH# (2024) Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
Cell Reports Medicine
[On the cover], [Backstory]

Roh K*, Noh J*, Kim Y, Jang Y, Kim J, Choi H, Lee Y, Ji M, Kang D, Kim MS, Paik MJ, Chung J, Kim JH#, and C Kang# (2023) Lysosomal control of senescence and inflammation through cholesterol partitioning
Nature Metabolism

Kang D*, Lee J*, Jung J, Carlson BA, Chang MJ, Chang CB, Kang SB, Lee BC, Gladyshev VN, Hatfield DL, Lee BJ#, and Kim JH# (2022) Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Nature Communications

Cho Y*, Kim HS*, Kang D, Kim H, Lee N, Yun J, Kim YJ , Lee KM , Kim J, Kim HR, Hwang YI, Jo CH, and Kim JH# (2021). CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition

Science Advances

Kim H*, Cho Y*, Kim HS, Kang D, Cheon D, Kim YJ, Chang MJ, Lee KM, Chang CB, Kang SB, Kang HG, and Kim JH# (2020). A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression.

Nature Communications

Kim S*, Han S*, Kim Y, Kim HS, Gu YR, Kang D, Cho Y, Kim H, Lee J, Seo Y, Chang MJ, Chang CB, Kang SB, and Kim JH# (2019). Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation.

Nature Communications


Kang D*, Shin J*, Cho Y, Kim HS, Gu YR, Kim H, You KT, Chang MJ, Chang CB, Kang SB, Kim JS, Kim VN, and Kim JH# (2019). Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development.

Science Translational Medicine


Won Y, Shin Y, Chun CH, Cho Y, Ha CW, Kim JH#, and Chun JS# (2016). Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis.

Annals of the Rheumatic Diseases


Lee M, Won Y, Shin Y, Kim JH#, and Chun JS# (2015). Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis.

Osteoarthritis and Cartilage


Kim JH, Lee G, Won Y, Lee M, Kwak JS, Chun CH, Chun JS# (2015). Matrix crosslinking-mediated mechanotransduction promotes post-traumatic osteoarthritis.

Proceedings of the National Academy of Sciences


Kim JH, Jeon J, Shin M, Won Y, Lee M, Kwak JS, Lee G, Rhee J, Ryu JH, Chun CH, and Chun JS# (2014). Regulation of the catabolic cascade in osteoarthritis by the zinc•ZIP8•MTF1 axis.




Jeong S*, Afroz S*, Kang D, Noh J, Suh J, Kim JH, You HJ, Kang HG#, Kim YJ#, and Kim JH# (2023) Sarcoma Immunotherapy: Confronting Present Hurdles and Unveiling Upcoming Opportunities
Molecules and Cells

Bang J, Kang D, Jung J, Yoo TJ, Shim MS, Gladyshev VN, Tsuji PA, Hatfield DL, Kim JH#, and Lee BJ# (2022) SEPHS1: Its evolution, function and roles in development and diseases.
Archives of biochemistry and biophysics

Cho Y*, Jeong S*, Kim H, Kang D, Lee J, Kang SB#, and Kim JH# (2021). Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions.

Experimental & Molecular Medicine

Kang D*, Lee J*, Wu C, Guo X, Lee BJ, Chun JS, and Kim JH# (2020). The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies.

Experimental & Molecular Medicine

Kim H, Kang D, Cho Y, and Kim JH# (2015). Epigenetic regulation of chondrocyte catabolism and anabolism in osteoarthritis.

Molecules and Cells


#Full List of Publications

Chun HJ*, Kim ER*, Lee M*, Choi DH, Kim SH, Shin E, Kim JH, Cho JW, Han DH#, Cha BS#, and Lee YH# (2023) Increased expression of sodium-glucose cotransporter 2 and O-GlcNAcylation in hepatocytes drives non-alcoholic steatohepatitis

Sohn HS*, Choi JW*, Jhun J, Kwon SP, Jung M, Yong S, Na HS, Kim JH, Cho ML#, and BS Kim# (2022) Tolerogenic nanoparticles induce type II collagen–specific regulatory T cells and ameliorate osteoarthritis
Science Advances

Yoo TJ, Shim MS, Bang J, Kim JH, and BJ Lee# (2022) SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells
Biology Open

Kim S, Lee K, Choi YS, Ku J, Kim H, Kharbash R, Yoon J, Lee YS, Kim JH, Lee YJ#, and Kim YS# (2022) Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
Cell Reports

Jung J, Kim Y, Na J, Qiao L, Bang J, Kwon D, Yoo TJ, Kang D, Kim LK, Carlson BA, Hatfield DL, Kim JH#, and Lee BJ# (2021) Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction

International Journal of Molecular Sciences

Bang J, Han M, Yoo T, Qiao L, Jung J, Na J, Carlson BA, Gladyshev VN, Hatfield DL, Kim JH, Kim LK#, and Lee BJ# (2021) Identification of signaling pathways for early embryonic lethality and developmental retardation in Sephs1-/- mice
International Journal of Molecular Sciences

Oh HK, Park MS, Choi SW, Jeong DU, Kim BJ, Kim JA, Choi HJ, Lee J, Cho YS, Kim JH, Seong JK, Choi BH, Min BH, and Kim DW# (2021) Suppression of Osteoarthritis progression by post-natal Induction of Nkx3.2Biochemical and Biophysical Research Communications

Lee Y*, Kim J*, Kim MS*, Kwon Y, Shin S, Yi H, Kim H, Chang MJ, Chang CB, Kang SB, Kim VN, Kim JH, Kim JS, Elledge SJ, and Kang C# (2021). Coordinate regulation of the senescent state by selective autophagy.

Developmental Cell

Seo J, Park YS, Kweon TH, Kang J, Son S, Kim HB, Seo YR, Kang MJ, Yi EC, Lee YH, Kim JH, Park B, Yang WH, and Cho JW# (2021). O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity,

Frontiers in Immunology


Choi DW*, Roh YJ*, Kim S*, Lee HM, Kim M, Shin D, Park JH, Cho Y, Park HH, Ok YS, Kang D, Kim JH, Tarrago L, Danial NN, Gladyshev VN, Min PK#, and Lee BC# (2021). Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues.

Biosensors and Bioelectronics


Lee SH, Lee N, Kim S, Lee J, Choi W, Yu SS, Kim JH, and Kim S# (2019). Intramuscular delivery of HGF-expressing recombinant AAV improves muscle integrity and alleviates neurological symptoms in the nerve crush and SOD1-G93A transgenic mouse models.

Biochemical and Biophysical Research Communications


Lee SH, Kim S, Lee N, Lee J, Yu SS, Kim JH, and Kim S# (2019). Intrathecal delivery of recombinant AAV1 encoding hepatocyte growth factor improves motor functions and protects neuromuscular system in the nerve crush and SOD1-G93A transgenic mouse models.

Acta Neuropathologica Communications


Na J*, Jung J*, Bang J, Lu Q, Carlson BA, Guo X, Gladyshev VN, Kim JH, Hatfield DL, and Lee BJ# (2018). Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation.

Free Radical Biology and Medicine

Kim JH*, Sim JH*, Lee S, Seol MA, Ye SK, Shin HM, Lee EB, Lee YJ, Choi YJ, Yoo WH, Kim JH, Kim WU, Lee DS, Kim JH, Kang I, Kang SW#, and Kim HR# (2017). Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand.

Frontiers In Immunology


Rhee J, Park SH, Kim SK, Kim JH, Ha CW, Chun CH, and Chun JS# (2017). Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.

Annals of the Rheumatic Diseases


Oh H*, Kwak JS*, Yang S, Gong MK, Kim JH, Rhee J, Kim SK, Kim HE, Ryu JH, and Chun JS# (2015). Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD+-SIRT axis in articular chondrocytes is involved in osteoarthritis.

Osteoarthritis and Cartilage


Yang S*, Ryu JH*, Oh H, Jeon J, Kwak JS, Kim JH, Kim HA, Chun CH, and Chun JS# (2013). Nampt (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.

Annals of the Rheumatic Diseases

Notbohm J#, Kim JH, Asthagiri AR, and Ravichandran G (2012). Three-dimensional analysis of the effect of epidermal growth factor on cell-cell adhesion in epithelial cell clusters.

Biophysics Journal


Rhee J, Ryu JH, Kim JH, Chun CH, and Chun JS# (2012). α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.

Journal of Biological Chemistry

Jeon J, Oh H, Lee G, Ryu JH, Rhee J, Kim JH, Chung KH, Song WK, Chun CH, and Chun JS# (2011). Cytokine-like 1 knock-out mice (Cytl1-/-) show normal cartilage and bone development but exhibit augmented osteoarthritic cartilage destruction.

Journal of Biological Chemistry

Kim JH and Asthagiri AR# (2011). Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation.

Journal of Cell Science

Kim JH, Dooling L, and Asthagiri AR# (2010). Intercellular mechanotransduction during multicellular morphodynamics.

Journal of Royal Society Interface

Kim JH, Kushiro K, Graham NA, and Asthagiri AR# (2009). Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth.

Proceedings of the National Academy of Sciences

Ko CC, Oyen M, Fallgatter AM, Kim JH, Friction J, and Hu WS# (2006). Mechanical properties and cytocompatibility of biomimetic hydroxyapatite-gelatin nanocomposites.

Journal of Materials Research

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