Cho Y*, Kim H*, Yook G*, Yong S, Kim S, Lee N, Kim YJ, Kim J, Kim TW, Chang MJ, Lee KM, Chang CB, Kang SB, Kim JH# (2024) IRF1 deficiency predisposes cartilage to accumulate DNA damage and promotes osteoarthritis development

Arthritis & Rheumatology

https://acrjournals.onlinelibrary.wiley.com/doi/abs/10.1002/art.42815

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YJ Kim*, HG Kang, and Kim JH# (2024) Hunting for the vulnerability in chondrosarcoma by tracing metabolic and genetic links

Cell Reports Medicine

https://www.sciencedirect.com/science/article/pii/S2666379123006146

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Suh J*, Kim H*, Min J, Yeon HJ, Hemberg M, Scimeca L, Wu MR, Kang HG, Kim YJ#, and Kim JH# (2024) Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
Cell Reports Medicine
https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(23)00559-1
[On the cover]

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Chun HJ*, Kim ER*, Lee M*, Choi DH, Kim SH, Shin E, Kim JH, Cho JW, Han DH#, Cha BS#, and Lee YH# (2023) Increased expression of sodium-glucose cotransporter 2 and O-GlcNAcylation in hepatocytes drives non-alcoholic steatohepatitis
Metabolism
https://www.sciencedirect.com/science/article/pii/S0026049523002160?via%3Dihub
 

Jeong S*, Afroz S*, Kang D, Noh J, Suh J, Kim JH, You HJ, Kang HG#, Kim YJ#, and Kim JH# (2023) Sarcoma Immunotherapy: Confronting Present Hurdles and Unveiling Upcoming Opportunities
Molecules and Cells
https://www.molcells.org/journal/view.html?doi=10.14348/molcells.2023.0079

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Roh K*, Noh J*, Kim Y, Jang Y, Kim J, Choi H, Lee Y, Ji M, Kang D, Kim MS, Paik MJ, Chung J, Kim JH#, and C Kang# (2023) Lysosomal control of senescence and inflammation through cholesterol partitioning

Nature Metabolism

https://www.nature.com/articles/s42255-023-00747-5

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Sohn HS*, Choi JW*, Jhun J, Kwon SP, Jung M, Yong S, Na HS, Kim JH, Cho ML#, and BS Kim# (2022) Tolerogenic nanoparticles induce type II collagen–specific regulatory T cells and ameliorate osteoarthritis
Science Advances  
https://www.science.org/doi/10.1126/sciadv.abo5284

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Bang J, Kang D, Jung J, Yoo TJ, Shim MS, Gladyshev VN, Tsuji PA, Hatfield DL, Kim JH#, and Lee BJ# (2022) SEPHS1: Its evolution, function and roles in development and diseases.

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Kang D*, Lee J*, Jung J, Carlson BA, Chang MJ, Chang CB, Kang SB, Lee BC, Gladyshev VN, Hatfield DL, Lee BJ#, and Kim JH# (2022) Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Nature Communications

https://www.nature.com/articles/s41467-022-28385-7

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Yoo TJ, Shim MS, Bang J, Kim JH, and BJ Lee# (2022) SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells
Biology Open
https://journals.biologists.com/bio/article/11/8/bio059295/276166/SPS1-deficiency-triggered-PGRP-LC-and-Toll

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Kim S, Lee K, Choi YS, Ku J, Kim H, Kharbash R, Yoon J, Lee YS, Kim JH, Lee YJ#, and Kim YS# (2022) Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
Cell Reports
https://www.sciencedirect.com/science/article/pii/S2211124722009913
 

Cho Y*, Kim HS*, Kang D, Kim H, Lee N, Yun J, Kim YJ , Lee KM , Kim J, Kim HR, Hwang YI, Jo CH, and Kim JH# (2021). CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition

Science Advances

https://www.science.org/doi/10.1126/sciadv.abg6069

​

Jung J, Kim Y, Na J, Qiao L, Bang J, Kwon D, Yoo TJ, Kang D, Kim LK, Carlson BA, Hatfield DL, Kim JH#, and Lee BJ# (2021) Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction

International Journal of Molecular Sciences 

https://www.mdpi.com/1422-0067/22/21/11646

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Cho Y*, Jeong S*, Kim H, Kang D, Lee J, Kang SB#, and Kim JH# (2021). Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions.

Experimental & Molecular Medicine

https://www.nature.com/articles/s12276-021-00710-y

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Bang J, Han M, Yoo T, Qiao L, Jung J, Na J, Carlson BA, Gladyshev VN, Hatfield DL, Kim JH, Kim LK#, and Lee BJ# (2021) Identification of signaling pathways for early embryonic lethality and developmental retardation in Sephs1-/- mice
International Journal of Molecular Sciences 
https://www.mdpi.com/1422-0067/22/21/11647

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Oh HK, Park MS, Choi SW, Jeong DU, Kim BJ, Kim JA, Choi HJ, Lee J, Cho YS, Kim JH, Seong JK, Choi BH, Min BH, and Kim DW# (2021) Suppression of Osteoarthritis progression by post-natal Induction of Nkx3.2Biochemical and Biophysical Research Communications

https://www.sciencedirect.com/science/article/pii/S0006291X21011104?via%3Dihub

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Lee Y*, Kim J*, Kim MS*, Kwon Y, Shin S, Yi H, Kim H, Chang MJ, Chang CB, Kang SB, Kim VN, Kim JH, Kim JS, Elledge SJ, and Kang C# (2021). Coordinate regulation of the senescent state by selective autophagy.

Developmental Cell

https://www.cell.com/developmental-cell/fulltext/S1534-5807(21)00317-8

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Seo J, Park YS, Kweon TH, Kang J, Son S, Kim HB, Seo YR, Kang MJ, Yi EC, Lee YH, Kim JH, Park B, Yang WH, and Cho JW# (2021). O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity,

Frontiers in Immunology  

https://www.frontiersin.org/article/10.3389/fimmu.2020.589259

 

Choi DW*, Roh YJ*, Kim S*, Lee HM, Kim M, Shin D, Park JH, Cho Y, Park HH, Ok YS, Kang D, Kim JH, Tarrago L, Danial NN, Gladyshev VN, Min PK#, and Lee BC# (2021). Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues.

Biosensors and Bioelectronics

https://www.sciencedirect.com/science/article/pii/S0956566321000671

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Kang D*, Lee J*, Wu C, Guo X, Lee BJ, Chun JS, and Kim JH# (2020). The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies.

Experimental & Molecular Medicine

https://www.nature.com/articles/s12276-020-0408-y

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Kim H*, Cho Y*, Kim HS, Kang D, Cheon D, Kim YJ, Chang MJ, Lee KM, Chang CB, Kang SB, Kang HG, and Kim JH# (2020). A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression.

Nature Communications

https://www.nature.com/articles/s41467-020-18817-7

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Lee SH, Lee N, Kim S, Lee J, Choi W, Yu SS, Kim JH, and Kim S# (2019). Intramuscular delivery of HGF-expressing recombinant AAV improves muscle integrity and alleviates neurological symptoms in the nerve crush and SOD1-G93A transgenic mouse models.

Biochemical and Biophysical Research Communications

https://www.sciencedirect.com/science/article/pii/S0006291X19314718

 

Kim S*, Han S*, Kim Y, Kim HS, Gu YR, Kang D, Cho Y, Kim H, Lee J, Seo Y, Chang MJ, Chang CB, Kang SB, and Kim JH# (2019). Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation.

Nature Communications

https://www.nature.com/articles/s41467-019-12910-2

 

Kang D*, Shin J*, Cho Y, Kim HS, Gu YR, Kim H, You KT, Chang MJ, Chang CB, Kang SB, Kim JS, Kim VN, and Kim JH# (2019). Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development.

Science Translational Medicine

https://stm.sciencemag.org/content/11/486/eaar6659

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Lee SH, Kim S, Lee N, Lee J, Yu SS, Kim JH, and Kim S# (2019). Intrathecal delivery of recombinant AAV1 encoding hepatocyte growth factor improves motor functions and protects neuromuscular system in the nerve crush and SOD1-G93A transgenic mouse models.

Acta Neuropathologica Communications

https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0737-z

 

Na J*, Jung J*, Bang J, Lu Q, Carlson BA, Guo X, Gladyshev VN, Kim JH, Hatfield DL, and Lee BJ# (2018). Selenophosphate synthetase 1 and its role in redox homeostasis, defense and proliferation.

Free Radical Biology and Medicine

https://www.sciencedirect.com/science/article/pii/S0891584918307706

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Kim JH*, Sim JH*, Lee S, Seol MA, Ye SK, Shin HM, Lee EB, Lee YJ, Choi YJ, Yoo WH, Kim JH, Kim WU, Lee DS, Kim JH, Kang I, Kang SW#, and Kim HR# (2017). Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand.

Frontiers In Immunology

https://www.frontiersin.org/articles/10.3389/fimmu.2017.01376/full

 

Rhee J, Park SH, Kim SK, Kim JH, Ha CW, Chun CH, and Chun JS# (2017). Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.

Annals of the Rheumatic Diseases

https://ard.bmj.com/content/76/2/427

 

Won Y, Shin Y, Chun CH, Cho Y, Ha CW, Kim JH#, and Chun JS# (2016). Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis.

Annals of the Rheumatic Diseases

https://ard.bmj.com/content/75/11/2045

​

Oh H*, Kwak JS*, Yang S, Gong MK, Kim JH, Rhee J, Kim SK, Kim HE, Ryu JH, and Chun JS# (2015). Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD+-SIRT axis in articular chondrocytes is involved in osteoarthritis.

Osteoarthritis and Cartilage

https://www.sciencedirect.com/science/article/pii/S1063458415012522

​

Lee M, Won Y, Shin Y, Kim JH#, and Chun JS# (2015). Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis.

Osteoarthritis and Cartilage

https://www.sciencedirect.com/science/article/pii/S1063458415012595?via%3Dihub

​

Kim JH, Lee G, Won Y, Lee M, Kwak JS, Chun CH, Chun JS# (2015). Matrix crosslinking-mediated mechanotransduction promotes post-traumatic osteoarthritis.

Proceedings of the National Academy of Sciences

https://www.pnas.org/content/112/30/9424

​

Kim H, Kang D, Cho Y, and Kim JH# (2015). Epigenetic regulation of chondrocyte catabolism and anabolism in osteoarthritis.

Molecules and Cells

http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2015.0200

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Kim JH, Jeon J, Shin M, Won Y, Lee M, Kwak JS, Lee G, Rhee J, Ryu JH, Chun CH, and Chun JS# (2014). Regulation of the catabolic cascade in osteoarthritis by the zinc•ZIP8•MTF1 axis.

Cell

https://www.cell.com/cell/fulltext/S0092-8674(14)00017-8

​

Yang S*, Ryu JH*, Oh H, Jeon J, Kwak JS, Kim JH, Kim HA, Chun CH, and Chun JS# (2013). Nampt (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.

Annals of the Rheumatic Diseases

https://ard.bmj.com/content/74/3/595

​

Notbohm J#, Kim JH, Asthagiri AR, and Ravichandran G (2012). Three-dimensional analysis of the effect of epidermal growth factor on cell-cell adhesion in epithelial cell clusters.

Biophysics Journal

https://www.sciencedirect.com/science/article/pii/S0006349512002184

 

Rhee J, Ryu JH, Kim JH, Chun CH, and Chun JS# (2012). α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.

Journal of Biological Chemistry

https://www.sciencedirect.com/science/article/pii/S0021925820531013

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Jeon J, Oh H, Lee G, Ryu JH, Rhee J, Kim JH, Chung KH, Song WK, Chun CH, and Chun JS# (2011). Cytokine-like 1 knock-out mice (Cytl1-/-) show normal cartilage and bone development but exhibit augmented osteoarthritic cartilage destruction.

Journal of Biological Chemistry

https://www.sciencedirect.com/science/article/pii/S0021925820503268

​

Kim JH and Asthagiri AR# (2011). Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation.

Journal of Cell Science

https://doi.org/10.1242/jcs.078394

​

Kim JH, Dooling L, and Asthagiri AR# (2010). Intercellular mechanotransduction during multicellular morphodynamics.

Journal of Royal Society Interface

https://doi.org/10.1098/rsif.2010.0066.focus

​

Kim JH, Kushiro K, Graham NA, and Asthagiri AR# (2009). Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth.

Proceedings of the National Academy of Sciences

https://www.pnas.org/content/106/27/11149

​

Ko CC, Oyen M, Fallgatter AM, Kim JH, Friction J, and Hu WS# (2006). Mechanical properties and cytocompatibility of biomimetic hydroxyapatite-gelatin nanocomposites.

Journal of Materials Research 

https://doi.org/10.1557/jmr.2006.0394